Chapter 4. Nuclear Receptor-Mediated Regulation of Drug Transporters
- Wen Xie2,3
Published Online: 14 MAY 2008
DOI: 10.1002/9780470409107.ch4
Copyright © 2009 John Wiley & Sons, Inc.
Book Title
Nuclear Receptors in Drug Metabolism
Additional Information
How to Cite
Burk, O. (2008) Nuclear Receptor-Mediated Regulation of Drug Transporters, in Nuclear Receptors in Drug Metabolism (ed W. Xie), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470409107.ch4
Editor Information
- 2
Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, PA, USA
- 3
Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, USA
Publication History
- Published Online: 14 MAY 2008
- Published Print: 24 OCT 2008
ISBN Information
Print ISBN: 9780470086797
Online ISBN: 9780470409107
- Summary
- Chapter
- References
Keywords:
- drug transporter nuclear receptor-mediated regulation;
- drug transporter induction and PXR and CAR activation;
- PXR- and CAR-dependent drug molecular mechanism
Summary
This chapter contains sections titled:
Introduction
Drug Transporters
Induction of Drug Transporters by Activation of PXR and CAR
Induction of Drug Transporters by Activation of PPARα
Molecular Mechanism of PXR- and CAR-Dependent Drug Transporter Regulation
Induction of Drug Transporter Expression and Drug Disposition
Conclusions and Future Perspectives
References