Chapter 5. Structure and Function of PXR and CAR

  1. Wen Xie2,3
  1. X. Edward Zhou,
  2. H. Eric Xu

Published Online: 14 MAY 2008

DOI: 10.1002/9780470409107.ch5

Book Title

Nuclear Receptors in Drug Metabolism

Nuclear Receptors in Drug Metabolism

Additional Information

How to Cite

Zhou, X. E. and Xu, H. E. (2008) Structure and Function of PXR and CAR, in Nuclear Receptors in Drug Metabolism (ed W. Xie), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470409107.ch5

Editor Information

  1. 2

    Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, PA, USA

  2. 3

    Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, USA

Author Information

  1. Laboratory of Structural Sciences, Van Andel Research Institute, Grand Rapids, MI, USA

Publication History

  1. Published Online: 14 MAY 2008
  2. Published Print: 24 OCT 2008

ISBN Information

Print ISBN: 9780470086797

Online ISBN: 9780470409107

SEARCH

CHAPTER TOOLS

Get PDF (2380K)

Keywords:

  • human PXR LBD crystal structures;
  • human CAR ligand binding pocket;
  • CAR/RXR dimer interface - humans and mouse CAR structures

Summary

This chapter contains sections titled:

  • Introduction

  • Structure and Function of PXR

  • Structure and Function of CAR

  • Concluding Remarks

  • References

Get PDF (2380K)