Chapter 6. Xenobiotic Receptor Cofactors and Coregulators

  1. Wen Xie2,3
  1. John Y. L. Chiang

Published Online: 14 MAY 2008

DOI: 10.1002/9780470409107.ch6

Book Title

Nuclear Receptors in Drug Metabolism

Nuclear Receptors in Drug Metabolism

Additional Information

How to Cite

Chiang, J. Y. L. (2008) Xenobiotic Receptor Cofactors and Coregulators, in Nuclear Receptors in Drug Metabolism (ed W. Xie), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470409107.ch6

Editor Information

  1. 2

    Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, PA, USA

  2. 3

    Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, USA

Author Information

  1. Department of Microbiology, Immunology and Biochemistry, Northeastern Ohio Universities College of Medicine, Rootstown, OH, USA

Publication History

  1. Published Online: 14 MAY 2008
  2. Published Print: 24 OCT 2008

ISBN Information

Print ISBN: 9780470086797

Online ISBN: 9780470409107

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CHAPTER TOOLS

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Keywords:

  • xenobiotic receptor cofactors and coregulators;
  • cholesterol metabolism and PXR regulation;
  • PXR and CAR nuclear receptor interactions

Summary

This chapter contains sections titled:

  • Regulation of PXR and CAR Nuclear Translocation

  • Nuclear Receptor Coregulators and Epigenetic Regulation of Gene Transcription

  • PXR and CAR Cross Talk With Other Nuclear Receptors and Transcription Factors

  • PXR and CAR Regulation of Lipid and Glucose Homeostasis

  • Conclusion

  • References

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