Chapter 8. Nuclear Receptors and Drug–Drug Interactions with Prescription and Herbal Medicines

  1. Wen Xie4,5
  1. Rommel G. Tirona1,2,3,
  2. Richard B. Kim1,2,3

Published Online: 14 MAY 2008

DOI: 10.1002/9780470409107.ch8

Nuclear Receptors in Drug Metabolism

Nuclear Receptors in Drug Metabolism

How to Cite

Tirona, R. G. and Kim, R. B. (2008) Nuclear Receptors and Drug–Drug Interactions with Prescription and Herbal Medicines, in Nuclear Receptors in Drug Metabolism (ed W. Xie), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470409107.ch8

Editor Information

  1. 4

    Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, PA, USA

  2. 5

    Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, USA

Author Information

  1. 1

    Division of Clinical Pharmacology, The University of Western Ontario, Ontario, Canada

  2. 2

    Department of Medicine and Department of Physiology and Pharmacology, The University of Western Ontario, Ontario, Canada

  3. 3

    Schulich School of Medicine and Dentistry, The University of Western Ontario, Ontario, Canada

Publication History

  1. Published Online: 14 MAY 2008
  2. Published Print: 24 OCT 2008

ISBN Information

Print ISBN: 9780470086797

Online ISBN: 9780470409107

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Keywords:

  • nuclear receptors and drug–drug interactions with prescription;
  • pharmaceutical industry and pharmacology of induction;
  • induction-mediated drug interactions

Summary

This chapter contains sections titled:

  • Introduction

  • Prescription Drugs/Drug Classes Involved in Inductive Drug Interactions

  • Herbal Medicines Involved in Inductive Drug Interactions

  • Pharmacology of Induction

  • Clinical Aspects of Induction-Type Drug Interactions

  • Inhibition of Nuclear Receptors in Clinical Drug Interactions

  • Nuclear Receptor Mediated Drug Side Effects

  • Perspectives

  • References