1. Evolving Role of Mass Spectrometry in Drug Discovery and Development

  1. Ragu Ramanathan
  1. Dil M. Ramanathan Assistant Professor1 and
  2. Richard M. Lelacheur Laboratory Director2

Published Online: 14 MAY 2008

DOI: 10.1002/9780470409817.ch1

Mass Spectrometry in Drug Metabolism and Pharmacokinetics

Mass Spectrometry in Drug Metabolism and Pharmacokinetics

How to Cite

Ramanathan, D. M. and Lelacheur, R. M. (2008) Evolving Role of Mass Spectrometry in Drug Discovery and Development, in Mass Spectrometry in Drug Metabolism and Pharmacokinetics (ed R. Ramanathan), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470409817.ch1

Editor Information

  1. Bristol-Myers Squibb Pharmaceutical Research Institute, Department of Biotransformation, Pharmaceutical Candidate Optimization, Princeton, NJ, USA

Author Information

  1. 1

    Kean University, New Jersey Center for Science, Technology & Mathematics Education, Union, NJ, USA

  2. 2

    Taylor Technology, Inc., Princeton, NJ, USA

Publication History

  1. Published Online: 14 MAY 2008
  2. Published Print: 12 DEC 2008

ISBN Information

Print ISBN: 9780471751588

Online ISBN: 9780470409817

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Keywords:

  • drug discovery and development mass spectrometry;
  • quantitative analysis mass spectrometry;
  • sample preparation/cleanup and column technology

Summary

This chapter contains sections titled:

  • Route to Market: Discovery and Development of New Drugs

  • Drug Metabolism and Pharmacokinetics in Drug Discovery and Development

  • Mass Spectrometry Fundamentals

  • Mass Spectrometry in Quantitative Analysis

  • Advances in Sample Preparation/Cleanup and Column Technology

  • Serial and Parallel LC–MS Approaches

  • Higher Throughput Quantitative Analysis without Liquid Chromatography

  • Mass Spectrometry in Qualitative Analysis

  • References