4. Applications of Quadrupole Time-of-Flight Mass Spectrometry in Reactive Metabolite Screening

  1. Ragu Ramanathan
  1. Jose M. Castro-Perez Laboratory Manager-Metabolite Profiling

Published Online: 14 MAY 2008

DOI: 10.1002/9780470409817.ch4

Mass Spectrometry in Drug Metabolism and Pharmacokinetics

Mass Spectrometry in Drug Metabolism and Pharmacokinetics

How to Cite

Castro-Perez, J. M. (2008) Applications of Quadrupole Time-of-Flight Mass Spectrometry in Reactive Metabolite Screening, in Mass Spectrometry in Drug Metabolism and Pharmacokinetics (ed R. Ramanathan), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470409817.ch4

Editor Information

  1. Bristol-Myers Squibb Pharmaceutical Research Institute, Department of Biotransformation, Pharmaceutical Candidate Optimization, Princeton, NJ, USA

Author Information

  1. Waters Corporation, Milford, MA, USA

Publication History

  1. Published Online: 14 MAY 2008
  2. Published Print: 12 DEC 2008

ISBN Information

Print ISBN: 9780471751588

Online ISBN: 9780470409817

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Keywords:

  • quadrupole time-of-flight mass spectrometry application;
  • exact mass measurements and high-resolution mass spectrometry;
  • reactive drug metabolism and Q-tof technology

Summary

This chapter contains sections titled:

  • Introduction

  • High-Resolution Chromatography

  • Time-of-Flight Mass Spectrometer

  • Exact Mass Measurements and High-Resolution Mass Spectrometry

  • Reactive Drug Metabolism and Q-TOF Technology

  • Summary

  • References