12. Identification of Signaling Pathways Involved During Differentiation

  1. Uma Lakshmipathy,
  2. Jonathan D. Chesnut and
  3. Bhaskar Thyagarajan
  1. Takumi Miura

Published Online: 17 APR 2009

DOI: 10.1002/9780470454923.ch12

Emerging Technology Platforms for Stem Cells

Emerging Technology Platforms for Stem Cells

How to Cite

Miura, T. (2009) Identification of Signaling Pathways Involved During Differentiation, in Emerging Technology Platforms for Stem Cells (eds U. Lakshmipathy, J. D. Chesnut and B. Thyagarajan), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470454923.ch12

Editor Information

  1. Primary and Stem Cell Systems, Invitrogen Corporation, 5781 Faraday Avenue, Carlsbad, CA 92008, USA

Author Information

  1. Department of Reproduction, Division of Reproductive Biology, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan

Publication History

  1. Published Online: 17 APR 2009
  2. Published Print: 18 MAR 2009

ISBN Information

Print ISBN: 9780470146934

Online ISBN: 9780470454923

SEARCH

Keywords:

  • signaling pathway identification;
  • modulation of cell cycle and p53 during differentiation in ES cells;
  • role of PI 3 k/A kt pathway in maintenance of ES cell pluripotency and viability

Summary

This chapter contains sections titled:

  • Introduction

  • The Usage of Large-Scale Transcriptome Analysis to Identify Transcripts from ES Cells

  • Modulation of Cell Cycle and P53 during Differentiation in ES Cells

  • Effects of the Retinoblastoma (RB)/E2F Pathway on Differentiation in ES Cells

  • Role of the PI3K/AKT Pathway in the Maintenance of ES Cell Pluripotency and Viability

  • Conclusions

  • References