Published Online: 30 JAN 2010
Copyright © 2010 John Wiley & Sons, Inc. All rights reserved.
Corsini Encyclopedia of Psychology
How to Cite
Gillespie, C. F., Hung, O. Y. and Burgess, K. A. 2010. Antidepressant Medications. Corsini Encyclopedia of Psychology. 1–2.
- Published Online: 30 JAN 2010
The observation that the induction of seizure activity was useful in the treatment of psychiatric illness (Fink, 2001) was initially appreciated in asylum patients treated with convulsion-inducing chemical agents such as camphor and metrazole and then later with insulin. The subsequent development of electrical methods of seizure induction and technical refinements to its application resulted in modern electroconvulsive therapy (ECT), the prototypic brain stimulation treatment and one of the most extensively validated treatments for depression.