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  1. Shawn E. Christ

Published Online: 30 JAN 2010

DOI: 10.1002/9780470479216.corpsy0675

Corsini Encyclopedia of Psychology

Corsini Encyclopedia of Psychology

How to Cite

Christ, S. E. 2010. Phenylketonuria. Corsini Encyclopedia of Psychology. 1–2.

Author Information

  1. University of Missouri-Columbia

Publication History

  1. Published Online: 30 JAN 2010


Phenylketonuria (PKU) is a rare genetic disorder characterized by an inability to metabolize phenylalanine, a common amino acid. Although its incidence and prevalence may vary based on geographical area, PKU occurs in approximately one in 15,000 individuals. The most common variation of PKU (often termed “classic” PKU) is an autosomal recessive condition with a locus on chromosome 12q.


  • phenylketonuria;
  • genetics;
  • development;
  • children;
  • prefrontal cortex