6. Wharton's Jelly-Derived Mesenchymal Stromal Cells

  1. Curtis L. Cetrulo MD,
  2. Kyle J. Cetrulo and
  3. Curtis L. Cetrulo Jr. MD
  1. Barbara Lutjemeier,
  2. Deryl L. Troyer DVM, PhD and
  3. Professor Mark L. Weiss

Published Online: 18 MAR 2010

DOI: 10.1002/9780470480151.ch6

Perinatal Stem Cells

Perinatal Stem Cells

How to Cite

Lutjemeier, B., Troyer, D. L. and Weiss, M. L. (2009) Wharton's Jelly-Derived Mesenchymal Stromal Cells, in Perinatal Stem Cells (eds C. L. Cetrulo, K. J. Cetrulo and C. L. Cetrulo), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470480151.ch6

Editor Information

  1. Division of Plastic and Reconstructive Surgery, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

Author Information

  1. Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, USA

Publication History

  1. Published Online: 18 MAR 2010
  2. Published Print: 15 JUL 2009

ISBN Information

Print ISBN: 9780470420843

Online ISBN: 9780470480151



  • Wharton's jelly-derived mesenchymal stromal cells;
  • MSCs isolated from Wharton's Jelly (WJ) and umbilical cord MSCs;
  • WJCs - sharing properties unique to fetal-derived MSCs


This chapter contains sections titled:

  • Mesenchymal Stromal Cells

  • Immunophenotype of Mesenchymal Stromal Cells

  • MSCs are Multipotent Cells

  • MSC and Stromal Support of the Stem Cell Niche

  • Defining Primitive Stromal Cells: Differences between Fetal and Adult MSCs

  • Umbilical Cord MSCs

  • Characterization of Wharton's Jelly Derived Cells

  • Other MSC-Like Cells from Umbilical Cord

  • Comparison of WJCs to Adult Derived MSCs

  • In Vitro Differentiation of WJCs

  • Comparison of WJCs to Fetal MSCs

  • Transplantation of WJCs

  • WJCs as Primitive Stromal Cells

  • Summary

  • Acknowledgments

  • References