12. Multidrug Resistance Reversal in Solid Tumors

  1. Ahcène Boumendjel2,
  2. Jean Boutonnat3,4 and
  3. Jacques Robert5
  1. Tatiana Bogush1 and
  2. Jacques Robert5

Published Online: 15 JUN 2009

DOI: 10.1002/9780470495131.ch12

ABC Transporters and Multidrug Resistance

ABC Transporters and Multidrug Resistance

How to Cite

Bogush, T. and Robert, J. (2009) Multidrug Resistance Reversal in Solid Tumors, in ABC Transporters and Multidrug Resistance (eds A. Boumendjel, J. Boutonnat and J. Robert), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470495131.ch12

Editor Information

  1. 2

    Université de Grenoble, Grenoble, France

  2. 3

    Institut Jean Roget, Université Joseph Fourier, Grenoble, France

  3. 4

    Hôpital Michallon de Grenoble, Grenoble, France

  4. 5

    Institut Bergonié, Université Victor Segalen, Bordeaux, France

Author Information

  1. 1

    Blokhin Cancer Research Center, Moscow, Russia

  2. 5

    Institut Bergonié, Université Victor Segalen, Bordeaux, France

Publication History

  1. Published Online: 15 JUN 2009
  2. Published Print: 13 JUL 2009

Book Series:

  1. Wiley Series in Drug Discovery and Development

Book Series Editors:

  1. Binghe Wang

ISBN Information

Print ISBN: 9780470227343

Online ISBN: 9780470495131

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Keywords:

  • multidrug resistance reversal in solid tumors;
  • MDR reversal in solid tumors - reasons for failure;
  • P-glycoprotein-mediated MDR - cancer cell mechanisms to thwart anticancer drug effects

Summary

This chapter contains sections titled:

  • Introduction

  • Clinical trials aimed at MDR reversal in solid tumors

  • MDR reversal in solid tumors: The reasons for a failure

  • Conclusions

  • References