13. ABC Superfamily Transporters at the Human Blood–Brain Barrier

  1. Ahcène Boumendjel6,
  2. Jean Boutonnat7,8 and
  3. Jacques Robert9
  1. Jean-Michel Scherrmann1,2,3,4,5

Published Online: 15 JUN 2009

DOI: 10.1002/9780470495131.ch13

ABC Transporters and Multidrug Resistance

ABC Transporters and Multidrug Resistance

How to Cite

Scherrmann, J.-M. (2009) ABC Superfamily Transporters at the Human Blood–Brain Barrier, in ABC Transporters and Multidrug Resistance (eds A. Boumendjel, J. Boutonnat and J. Robert), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470495131.ch13

Editor Information

  1. 6

    Université de Grenoble, Grenoble, France

  2. 7

    Institut Jean Roget, Université Joseph Fourier, Grenoble, France

  3. 8

    Hôpital Michallon de Grenoble, Grenoble, France

  4. 9

    Institut Bergonié, Université Victor Segalen, Bordeaux, France

Author Information

  1. 1

    Inserm, U 705, France

  2. 2

    CNRS, UMR 7157, France

  3. 3

    University Paris Diderot, Paris, France

  4. 4

    University Paris Descartes, Paris, France

  5. 5

    Hôpital Fernand, Widal, Paris Cedex 10, France

Publication History

  1. Published Online: 15 JUN 2009
  2. Published Print: 13 JUL 2009

Book Series:

  1. Wiley Series in Drug Discovery and Development

Book Series Editors:

  1. Binghe Wang

ISBN Information

Print ISBN: 9780470227343

Online ISBN: 9780470495131

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Keywords:

  • ABC superfamily transporters;
  • P-gp acting as gatekeeper in BBB;
  • ABC genetic polymorphisms at BBB

Summary

This chapter contains sections titled:

  • Introduction

  • The BBB in a normal physiological state

  • ABC transporters of the BBB

  • ABC genetic polymorphisms at the BBB

  • Regulation pathways of ABC proteins at the BBB

  • ABC transporters at the BBB in disease states

  • Conclusions

  • Acknowledgments

  • References