8. Reversal Agents for P-Glycoprotein-Mediated Multidrug Resistance

  1. Ahcène Boumendjel3,
  2. Jean Boutonnat4,5 and
  3. Jacques Robert6
  1. Hamid Morjani1 and
  2. Claudie Madoulet2

Published Online: 15 JUN 2009

DOI: 10.1002/9780470495131.ch8

ABC Transporters and Multidrug Resistance

ABC Transporters and Multidrug Resistance

How to Cite

Morjani, H. and Madoulet, C. (2009) Reversal Agents for P-Glycoprotein-Mediated Multidrug Resistance, in ABC Transporters and Multidrug Resistance (eds A. Boumendjel, J. Boutonnat and J. Robert), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470495131.ch8

Editor Information

  1. 3

    Université de Grenoble, Grenoble, France

  2. 4

    Institut Jean Roget, Université Joseph Fourier, Grenoble, France

  3. 5

    Hôpital Michallon de Grenoble, Grenoble, France

  4. 6

    Institut Bergonié, Université Victor Segalen, Bordeaux, France

Author Information

  1. 1

    MEDyC Unité, Federative Institute of Research Biomolecules, Reims Pharmacy School, Reims, France

  2. 2

    Laboratoire de Biochimie, Reims Pharmacy School, Reims Cedex, France

Publication History

  1. Published Online: 15 JUN 2009
  2. Published Print: 13 JUL 2009

Book Series:

  1. Wiley Series in Drug Discovery and Development

Book Series Editors:

  1. Binghe Wang

ISBN Information

Print ISBN: 9780470227343

Online ISBN: 9780470495131

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Keywords:

  • drug resistance - reasons for cancer therapy failure;
  • P-gp activity modulation;
  • immunization with synthetic P-gp-derived peptides

Summary

This chapter contains sections titled:

  • Introduction

  • Drugs extruded by P-gp and common substrates with other pumps

  • Modulation of P-gp activity

  • Conclusion

  • References