9. Reversal Agents of Multidrug Resistance Mediated by Multidrug Resistance-Associated Proteins (MRPs)

  1. Ahcène Boumendjel1,
  2. Jean Boutonnat2,3 and
  3. Jacques Robert4
  1. Ahcène Boumendjel1,
  2. Anne Florin2,3 and
  3. Jean Boutonnat2,3

Published Online: 15 JUN 2009

DOI: 10.1002/9780470495131.ch9

ABC Transporters and Multidrug Resistance

ABC Transporters and Multidrug Resistance

How to Cite

Boumendjel, A., Florin, A. and Boutonnat, J. (2009) Reversal Agents of Multidrug Resistance Mediated by Multidrug Resistance-Associated Proteins (MRPs), in ABC Transporters and Multidrug Resistance (eds A. Boumendjel, J. Boutonnat and J. Robert), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470495131.ch9

Editor Information

  1. 1

    Université de Grenoble, Grenoble, France

  2. 2

    Institut Jean Roget, Université Joseph Fourier, Grenoble, France

  3. 3

    Hôpital Michallon de Grenoble, Grenoble, France

  4. 4

    Institut Bergonié, Université Victor Segalen, Bordeaux, France

Author Information

  1. 1

    Université de Grenoble, Grenoble, France

  2. 2

    Institut Jean Roget, Université Joseph Fourier, Grenoble, France

  3. 3

    Hôpital Michallon de Grenoble, Grenoble, France

Publication History

  1. Published Online: 15 JUN 2009
  2. Published Print: 13 JUL 2009

Book Series:

  1. Wiley Series in Drug Discovery and Development

Book Series Editors:

  1. Binghe Wang

ISBN Information

Print ISBN: 9780470227343

Online ISBN: 9780470495131

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Keywords:

  • multidrug resistance-associated proteins and substrates or drugs extruded;
  • MRP activity inhibitor evaluating methods;
  • reversal agents of multidrug resistance mediated by MRPS

Summary

This chapter contains sections titled:

  • Introduction

  • Substrates or drugs extruded by multidrug resistance-associated proteins

  • Methods to evaluate inhibitors of MRP activity

  • MRP modulators

  • Other approaches to MRP Modulation

  • Conclusion

  • References