27. QSAR Studies of MMP Inhibitors

  1. Claudiu T. Supuran2 and
  2. Jean-Yves Winum3
  1. Tiziano Tuccinardi and
  2. Adriano Martinelli

Published Online: 4 NOV 2009

DOI: 10.1002/9780470508169.ch27

Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications

Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications

How to Cite

Tuccinardi, T. and Martinelli, A. (2009) QSAR Studies of MMP Inhibitors, in Drug Design of Zinc-Enzyme Inhibitors: Functional, Structural, and Disease Applications (eds C. T. Supuran and J.-Y. Winum), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470508169.ch27

Editor Information

  1. 2

    Laboratorio di Chimica Bioinorganica, Università degli Studi di Firenze, Polo Scientifico, Room 188, Via della Lastruccia 3, 50019 Sesto Fiorentino (Florence), Italy

  2. 3

    Institut des Biomolécules Max Mousseron (IBMM) UMR 5247 CNRS-UM1-UM2 Bãtiment de Recherche Max Mousseron, Ecole Nationale Supérieure de Chimie de Montpellier, 8 rue de l'Ecole Normale, 34296 Montpellier Cedex, France

Author Information

  1. Dipartimento di Scienze Farmaceutiche, Università di Pisa, Via Bonanno 6, 56126 Pisa, Italy

Publication History

  1. Published Online: 4 NOV 2009
  2. Published Print: 3 AUG 2009

Book Series:

  1. Wiley Series in Drug Discovery and Development

Book Series Editors:

  1. Binghe Wang

ISBN Information

Print ISBN: 9780470275009

Online ISBN: 9780470508169

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Keywords:

  • quantitative structure–activity relationship (QSAR) studies of MMP inhibitors;
  • QSAR - correlating structural or property descriptors of compounds with activities;
  • nonclassical QSAR methods

Summary

This chapter contains sections titled:

  • Introduction

  • QSAR Studies

  • Nonclassical QSAR Methods

  • 3D-QSAR Studies

  • Conclusions

  • References