Hormonal Control of Cell Death in a Sexually Dimorphic Song Nucleus in the Zebra Finch

  1. Gregory Bock Organizer and
  2. Maeve O'Connor
  1. Masakazu Konishi and
  2. Eugene Akutagawa

Published Online: 28 SEP 2007

DOI: 10.1002/9780470513422.ch11

Ciba Foundation Symposium 126 - Selective Neuronal Death

Ciba Foundation Symposium 126 - Selective Neuronal Death

How to Cite

Konishi, M. and Akutagawa, E. (2007) Hormonal Control of Cell Death in a Sexually Dimorphic Song Nucleus in the Zebra Finch, in Ciba Foundation Symposium 126 - Selective Neuronal Death (eds G. Bock and M. O'Connor), John Wiley & Sons, Ltd., Chichester, UK. doi: 10.1002/9780470513422.ch11

Author Information

  1. Division of Biology, 216–76, California Institute of Technology, Pasadena, CA 91125, USA

Publication History

  1. Published Online: 28 SEP 2007

ISBN Information

Print ISBN: 9780471910923

Online ISBN: 9780470513422

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Keywords:

  • hormonal control;
  • cell death;
  • sexually dimorphic song nucleus;
  • zebra finch;
  • nucleus robustus archistriatalis

Summary

The song control nucler of the brain of the male zebra finch (Poephila guttata) contain more neurons of larger cross-sectional area and more extensive innervation than those in the female. The sexual dimorphism of nucleus robustus archistriatalis (RA), one of the song nuclei, arises from neuronal atrophy and death in the female brain as well as from an increase in cell-body size and afferent terminals from other forebrain nuclei in the male. Subcutaneous implantation of a slow-release pelkt of oestrogen in a female chick not only prevents her RA neurons from dying but also promotes their growth and innervation. The masculinizing effects of oestrogen on RA appear to be limited to a period of 35–40 days after hatching. Oestrogen may act on RA neurons indirectly by promoting their innervation from other forebrain song nuclei.