Natural Product Chemistry in North-Eastern Brazil

  1. Derek J. Chadwick Organizer,
  2. Joan Marsh
  1. A. A. Craveiro,
  2. M. I. L. Machado,
  3. J. W. Alencar,
  4. F. J. A. Matos

Published Online: 28 SEP 2007

DOI: 10.1002/9780470514634.ch7

Ciba Foundation Symposium 185 - Ethnobotany and the Search for New Drugs

Ciba Foundation Symposium 185 - Ethnobotany and the Search for New Drugs

How to Cite

Craveiro, A. A., Machado, M. I. L., Alencar, J. W. and Matos, F. J. A. (2007) Natural Product Chemistry in North-Eastern Brazil, in Ciba Foundation Symposium 185 - Ethnobotany and the Search for New Drugs (eds D. J. Chadwick and J. Marsh), John Wiley & Sons, Ltd., Chichester, UK. doi: 10.1002/9780470514634.ch7

Author Information

  1. Laboratory of Natural Products/Department of Organic and Inorganic Chemistry, Universidade Federal do Ceará, Caixa Postal 6822, Campus do Pici, 60458-978, Fortaleza, Ceará, Brazil

Publication History

  1. Published Online: 28 SEP 2007

ISBN Information

Print ISBN: 9780471950240

Online ISBN: 9780470514634

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Keywords:

  • natural product chemistry;
  • oleanolic saponin;
  • living pharmacy;
  • essential oils;
  • ethnobotany

Summary

The north-eastern region of Brazil comprises about one third of the country's territory. It is a semi-arid region with a flora rich in aromatic, toxic and medicinal plants. Screening of aromatic plants led to the investigation of about 2000 samples of essential oils from plants from the region and from abroad. Studies done by the Universidade Federal do Ceará and other research groups in the region discovered several new substances with distinct pharmacological activities. Recent examples are: schultezin, hydroxy-bisabolol, trans-annonene, (–)-hardwickic acid, trans-cascarillone, nor-cucurbitacins, oleanolic saponin and chalcone dimer. A social programme called the Living Pharmacy was created to teach poor people how to cultivate and use medicinal plants correctly. A project to develop interaction between the university and industry also arose from these studies.