Chapter 10. Mass Spectrometry

  1. Robert J. Flanagan1,
  2. Andrew Taylor2,
  3. Ian D. Watson3,
  4. Robin Whelpton4

Published Online: 1 FEB 2008

DOI: 10.1002/9780470516294.ch10

Book Title

Fundamentals of Analytical Toxicology

Fundamentals of Analytical Toxicology

Additional Information

How to Cite

Flanagan, R. J., Taylor, A., Watson, I. D. and Whelpton, R. (2008) Mass Spectrometry, in Fundamentals of Analytical Toxicology, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470516294.ch10

Author Information

  1. 1

    Department of Clinical Biochemistry, King's College Hospital NHS Foundation Trust, London, UK

  2. 2

    Royal Surrey County Hospital, Guildford, Surrey, UK

  3. 3

    Department of Clinical Biochemistry, University Hospital Aintree, Liverpool, UK

  4. 4

    School of Biological and Chemical Sciences, Queen Mary, University of London, London, UK

Publication History

  1. Published Online: 1 FEB 2008
  2. Published Print: 25 JAN 2008

ISBN Information

Print ISBN: 9780470319345

Online ISBN: 9780470516294

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CHAPTER TOOLS

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Keywords:

  • molecular fragmentation patterns (‘fingerprints’);
  • three-dimensional quadrupolar potential field;
  • high ionization efficiency and vaporization;
  • stable isotope-labelled internal standards;
  • multiple reaction monitoring (MRM)

Summary

This chapter contains sections titled:

  • Introduction

  • Instrumentation

  • Presentation of mass spectral data

  • Gas chromatography-mass spectrometry

  • Liquid chromatography-mass spectrometry

  • Interpretation of mass spectra

  • Quantitative mass spectrometry

  • Summary

  • References

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