Chapter 15. Absorption, Distribution, Metabolism and Excretion of Xenobiotic Compounds

  1. Robert J. Flanagan1,
  2. Andrew Taylor2,
  3. Ian D. Watson3,
  4. Robin Whelpton4

Published Online: 1 FEB 2008

DOI: 10.1002/9780470516294.ch15

Book Title

Fundamentals of Analytical Toxicology

Fundamentals of Analytical Toxicology

Additional Information

How to Cite

Flanagan, R. J., Taylor, A., Watson, I. D. and Whelpton, R. (2008) Absorption, Distribution, Metabolism and Excretion of Xenobiotic Compounds, in Fundamentals of Analytical Toxicology, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470516294.ch15

Author Information

  1. 1

    Department of Clinical Biochemistry, King's College Hospital NHS Foundation Trust, London, UK

  2. 2

    Royal Surrey County Hospital, Guildford, Surrey, UK

  3. 3

    Department of Clinical Biochemistry, University Hospital Aintree, Liverpool, UK

  4. 4

    School of Biological and Chemical Sciences, Queen Mary, University of London, London, UK

Publication History

  1. Published Online: 1 FEB 2008
  2. Published Print: 25 JAN 2008

ISBN Information

Print ISBN: 9780470319345

Online ISBN: 9780470516294

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CHAPTER TOOLS

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Keywords:

  • drug metabolism and pharmacogenetics;
  • blood–brain barrier (BBB);
  • plasma protein displacement interaction;
  • tertiary amines and stereospecific oxidation;
  • proximal convoluted tubule (PCT)

Summary

This chapter contains sections titled:

  • Introduction

  • Routes of administration

  • Absorption

  • Distribution

  • Metabolism

  • Excretion

  • Summary

  • References

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