Chapter 3. Sample Preparation

  1. Robert J. Flanagan1,
  2. Andrew Taylor2,
  3. Ian D. Watson3,
  4. Robin Whelpton4

Published Online: 1 FEB 2008

DOI: 10.1002/9780470516294.ch3

Book Title

Fundamentals of Analytical Toxicology

Fundamentals of Analytical Toxicology

Additional Information

How to Cite

Flanagan, R. J., Taylor, A., Watson, I. D. and Whelpton, R. (2008) Sample Preparation, in Fundamentals of Analytical Toxicology, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470516294.ch3

Author Information

  1. 1

    Department of Clinical Biochemistry, King's College Hospital NHS Foundation Trust, London, UK

  2. 2

    Royal Surrey County Hospital, Guildford, Surrey, UK

  3. 3

    Department of Clinical Biochemistry, University Hospital Aintree, Liverpool, UK

  4. 4

    School of Biological and Chemical Sciences, Queen Mary, University of London, London, UK

Publication History

  1. Published Online: 1 FEB 2008
  2. Published Print: 25 JAN 2008

ISBN Information

Print ISBN: 9780470319345

Online ISBN: 9780470516294

SEARCH

CHAPTER TOOLS

Get PDF (388K)

Keywords:

  • mixed-mode stationary phase (MMP);
  • titrate water-soluble compounds;
  • quaternary ammonium compounds;
  • analyte uptake and internal standard loss;
  • derivatizing agent or other reagents

Summary

This chapter contains sections titled:

  • Introduction

  • Modes of sample preparation

  • Measurement of nonbound plasma concentrations

  • Hydrolysis of conjugated metabolites

  • Extraction of drugs from tissues

  • Derivatization

  • Summary

  • References

Get PDF (388K)