Chapter 6. Thin-Layer Chromatography

  1. Robert J. Flanagan1,
  2. Andrew Taylor2,
  3. Ian D. Watson3,
  4. Robin Whelpton4

Published Online: 1 FEB 2008

DOI: 10.1002/9780470516294.ch6

Book Title

Fundamentals of Analytical Toxicology

Fundamentals of Analytical Toxicology

Additional Information

How to Cite

Flanagan, R. J., Taylor, A., Watson, I. D. and Whelpton, R. (2008) Thin-Layer Chromatography, in Fundamentals of Analytical Toxicology, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470516294.ch6

Author Information

  1. 1

    Department of Clinical Biochemistry, King's College Hospital NHS Foundation Trust, London, UK

  2. 2

    Royal Surrey County Hospital, Guildford, Surrey, UK

  3. 3

    Department of Clinical Biochemistry, University Hospital Aintree, Liverpool, UK

  4. 4

    School of Biological and Chemical Sciences, Queen Mary, University of London, London, UK

Publication History

  1. Published Online: 1 FEB 2008
  2. Published Print: 25 JAN 2008

ISBN Information

Print ISBN: 9780470319345

Online ISBN: 9780470516294

SEARCH

CHAPTER TOOLS

Get PDF (318K)

Keywords:

  • poison screening procedures;
  • chromogenic chemical detection reagents;
  • development systems and visualization reagents;
  • rotational planar chromatography (RPC);
  • metabolic and toxicological studies

Summary

This chapter contains sections titled:

  • Introduction

  • Preparation of thin-layer plates

  • Sample application

  • Developing the chromatogram

  • Visualizing the chromatogram

  • Retention factor (Rf)

  • Toxi-Lab

  • High-performance thin-layer chromatography

  • Quantitative thin-layer chromatography

  • Summary

  • References

Get PDF (318K)