Chapter 25. Botanical Supplements and Hepatotoxicity

  1. Saura C. Sahu
  1. Shabana Khan1,
  2. Ikhlas Khan2 and
  3. Larry Walker3

Published Online: 27 FEB 2008

DOI: 10.1002/9780470516751.ch25

Hepatotoxicity

Hepatotoxicity

How to Cite

Khan, S., Khan, I. and Walker, L. (2007) Botanical Supplements and Hepatotoxicity, in Hepatotoxicity (ed S. C. Sahu), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470516751.ch25

Editor Information

  1. Division of Toxicology, Office of Toxicology, Office of Applied Research and Safety Assessment, Center for Food Safety and Applied Nutrition, US Food and Drug Administration, 8301 Muirkirk Road, Laurel, MD 20708, USA

Author Information

  1. 1

    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, PO Box 1848, University, MS 38677, USA

  2. 2

    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences and Department of Pharmacognosy, School of Pharmacy, University of Mississippi, PO Box 1848, University, MS 38677, USA

  3. 3

    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences and Department of Pharmacology, School of Pharmacy, University of Mississippi, PO Box 1848, University, MS 38677, USA

Publication History

  1. Published Online: 27 FEB 2008
  2. Published Print: 14 DEC 2007

ISBN Information

Print ISBN: 9780470057162

Online ISBN: 9780470516751

SEARCH

Keywords:

  • conventional medical treatment effectiveness;
  • anti-aging therapies;
  • individual patient experience;
  • botanical dietary supplements;
  • myocardial infarction;
  • renal and hepatic failure;
  • botanical dietary supplements;
  • botanical supplement-associated liver injury;
  • botanical–drug interactions;
  • mediated drug metabolism

Summary

This chapter contains sections titled:

  • Introduction

  • General Safety Issues with Botanicals

  • Complexities in Chemical and Biological Characterization of Botanicals

  • Regulatory Aspects

  • Understanding Xenobiotic-induced Hepatotoxic Injury

  • Hepatotoxicity of Botanical Products

  • Conclusions

  • References