Chapter 6. Some Experimental Models of Liver Damage

  1. Saura C. Sahu
  1. Pablo Muriel

Published Online: 27 FEB 2008

DOI: 10.1002/9780470516751.ch6

Hepatotoxicity

Hepatotoxicity

How to Cite

Muriel, P. (2007) Some Experimental Models of Liver Damage, in Hepatotoxicity (ed S. C. Sahu), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470516751.ch6

Editor Information

  1. Division of Toxicology, Office of Toxicology, Office of Applied Research and Safety Assessment, Center for Food Safety and Applied Nutrition, US Food and Drug Administration, 8301 Muirkirk Road, Laurel, MD 20708, USA

Author Information

  1. Sección Externa de Farmacologia, Cinvestav-IPN, Apdo, Postal 14-740, México 07000, DF, México

Publication History

  1. Published Online: 27 FEB 2008
  2. Published Print: 14 DEC 2007

ISBN Information

Print ISBN: 9780470057162

Online ISBN: 9780470516751

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Keywords:

  • hepatic artery and portal vein;
  • metabolic and biochemical transformation;
  • gastrointestinal organs;
  • anatomical proximity;
  • potential hepatotoxic effects;
  • hepatic histopathology;
  • acute and chronic lesions;
  • nucleolar and nuclear abnormalities and megalocytes;
  • hepatic injury experimental models;
  • fatty acid molecules

Summary

This chapter contains sections titled:

  • Introduction

  • Carbon Tetrachloride

  • Hypomethylation

  • Acetaminophen (Paracetamol)

  • Cholestasis

  • Ischemia/Reperfusion Liver Injury

  • Hepatic Amebiasis

  • Concanavalin A

  • Alcoholic Liver Damage in Rats

  • Concluding Remarks

  • Acknowledgements

  • References