Chapter 2. General Overview of Signalling in the Nervous System

  1. Alexei Verkhratsky1 and
  2. Arthur Butt2

Published Online: 5 SEP 2007

DOI: 10.1002/9780470517796.ch2

Glial Neurobiology: A Textbook

Glial Neurobiology: A Textbook

How to Cite

Verkhratsky, A. and Butt, A. (2007) General Overview of Signalling in the Nervous System, in Glial Neurobiology: A Textbook, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470517796.ch2

Author Information

  1. 1

    University of Manchester, USA

  2. 2

    University of Portsmouth, USA

Publication History

  1. Published Online: 5 SEP 2007
  2. Published Print: 22 JUN 2007

ISBN Information

Print ISBN: 9780470015643

Online ISBN: 9780470517796



  • understanding brain function;
  • neuronal chemical synapse theory;
  • cell-to-cell signalling theory;
  • intracellular signalling and molecular cascades;
  • ionotropic receptors;
  • metabotropic receptors;
  • intracellular signalling and plasmalemmal receptors;
  • calcium signalling system;
  • volume transmission' (VT) - extracellular (EVT) or intracellular (IVT);
  • wiring and volume transmission


This chapter contains sections titled:

  • Intercellular signalling: Wiring and volume modes of transmission

  • Intracellular signalling