Chapter 12. Discovery of AZD1152: A Selective Inhibitor of Aurora-B Kinase with Potent Antitumor Activity
- Rongshi Li,
- Jeffrey A. Stafford
Published Online: 28 SEP 2009
DOI: 10.1002/9780470524961.ch12
Copyright © 2009 John Wiley & Sons, Inc.
Book Title
Kinase Inhibitor Drugs
Additional Information
How to Cite
Foote, K. M. and Mortlock, A. A. (2009) Discovery of AZD1152: A Selective Inhibitor of Aurora-B Kinase with Potent Antitumor Activity, in Kinase Inhibitor Drugs (eds R. Li and J. A. Stafford), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470524961.ch12
Editor Information
Takeda San Diego, Inc., San Diego, CA 92121, USA
Publication History
- Published Online: 28 SEP 2009
- Published Print: 2 OCT 2009
ISBN Information
Print ISBN: 9780470278291
Online ISBN: 9780470524961
- Summary
- Chapter
- References
Keywords:
- AZD 1152 discovery - selective inhibitor of Aurora-B kinase with potent antitumor activity;
- quinazolines substituted with aminothiazoles;
- screening cascade updated
Summary
This chapter contains sections titled:
Introduction
Anilinoquinazolines and Corresponding Pyrimidine and Pyridine Analogs
Crystallographic Studies
Quinazolines Substituted with Aminothiazoles or Aminothiophenes
The Screening Cascade Updated
Quinazolines Substituted with Aminopyrazoles
AZD1152
Summary
Acknowledgment
References