Chapter 14. DNA Damage by Phenoxyl Radicals

  1. Marc M. Greenberg
  1. Richard A. Manderville

Published Online: 28 SEP 2009

DOI: 10.1002/9780470526279.ch14

Radical and Radical Ion Reactivity in Nucleic Acid Chemistry

Radical and Radical Ion Reactivity in Nucleic Acid Chemistry

How to Cite

Manderville, R. A. (2009) DNA Damage by Phenoxyl Radicals, in Radical and Radical Ion Reactivity in Nucleic Acid Chemistry (ed M. M. Greenberg), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470526279.ch14

Editor Information

  1. Department of Chemistry, Johns Hopkins University, Baltimore, MD 21218, USA

Author Information

  1. Departments of Chemistry and Toxicology, University of Guelph, Guelph, Ontario, Canada N1G 2W1

Publication History

  1. Published Online: 28 SEP 2009
  2. Published Print: 18 SEP 2009

Book Series:

  1. Wiley Series of Reactive Intermediates in Chemistry and Biology

Book Series Editors:

  1. Steven E. Rokita

ISBN Information

Print ISBN: 9780470255582

Online ISBN: 9780470526279

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Keywords:

  • DNA damage by phenoxyl radicals;
  • covalent DNA adduction;
  • carbon-bound C8-phenolic-deoxyguanosine adducts

Summary

This chapter contains sections titled:

  • Introduction

  • Oxidation of Phenols

  • Oxidative DNA Damage

  • Covalent DNA Adduction

  • Carbon-Bound C8-Phenolic-Deoxyguanosine Adducts

  • Conclusions

  • Future Prospects

  • Acknowledgments

  • References