Chapter 4. Reactivity of Nucleic Acid Sugar Radicals

  1. Marc M. Greenberg
  1. Chryssostomos Chatgilialoglu

Published Online: 28 SEP 2009

DOI: 10.1002/9780470526279.ch4

Radical and Radical Ion Reactivity in Nucleic Acid Chemistry

Radical and Radical Ion Reactivity in Nucleic Acid Chemistry

How to Cite

Chatgilialoglu, C. (2009) Reactivity of Nucleic Acid Sugar Radicals, in Radical and Radical Ion Reactivity in Nucleic Acid Chemistry (ed M. M. Greenberg), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470526279.ch4

Editor Information

  1. Department of Chemistry, Johns Hopkins University, Baltimore, MD 21218, USA

Author Information

  1. ISOF, Consiglio Nazionale delle Richerche, 40129 Bologna, Italy

Publication History

  1. Published Online: 28 SEP 2009
  2. Published Print: 18 SEP 2009

Book Series:

  1. Wiley Series of Reactive Intermediates in Chemistry and Biology

Book Series Editors:

  1. Steven E. Rokita

ISBN Information

Print ISBN: 9780470255582

Online ISBN: 9780470526279

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Keywords:

  • nucleic acid sugar radical reactivity;
  • oxidation of C2′ position;
  • 5′-aldehyde terminus and oxidation lesions

Summary

This chapter contains sections titled:

  • Introduction

  • Oxidation of the C1′ Position

  • Oxidation of the C2′ Position

  • Oxidation of the C3′ Position

  • Oxidation of the C4′ Position

  • Oxidation of the C5′ Position

  • Conclusions

  • References