5. Intracellular Signal Transduction Cascades

  1. David J. Matthews and
  2. Mary E. Gerritsen

Published Online: 11 MAR 2010

DOI: 10.1002/9780470555293.ch5

Targeting Protein Kinases for Cancer Therapy

Targeting Protein Kinases for Cancer Therapy

How to Cite

Matthews, D. J. and Gerritsen, M. E. (2010) Intracellular Signal Transduction Cascades, in Targeting Protein Kinases for Cancer Therapy, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470555293.ch5

Author Information

  1. So. San Francisco, California, USA

Publication History

  1. Published Online: 11 MAR 2010
  2. Published Print: 27 JAN 2010

ISBN Information

Print ISBN: 9780470229651

Online ISBN: 9780470555293

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Keywords:

  • intracellular signal transduction cascades;
  • mTOR (mammalian target of rapamycin, FRAP) – ancient protein kinase;
  • PIM kinases

Summary

This chapter contains sections titled:

  • The PI3K/PTEN Pathway

  • mTOR Signaling

  • MAPK Signaling Pathways

  • PIM Kinases

  • Protein Kinase C

  • References