Chapter 19. Single-Gene and Whole-Genome Duplications and the Evolution of Protein–Protein Interaction Networks
- Gustavo Caetano-Anollés
Published Online: 12 JUL 2010
DOI: 10.1002/9780470570418.ch19
Copyright © 2010 Wiley-Blackwell.
Book Title
Evolutionary Genomics and Systems Biology
Additional Information
How to Cite
Amoutzias, G. and Van de Peer, Y. (2010) Single-Gene and Whole-Genome Duplications and the Evolution of Protein–Protein Interaction Networks, in Evolutionary Genomics and Systems Biology (ed G. Caetano-Anollés), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470570418.ch19
Editor Information
Bioinformatics Laboratory, Department of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA
Publication History
- Published Online: 12 JUL 2010
- Published Print: 1 MAR 2010
ISBN Information
Print ISBN: 9780470195147
Online ISBN: 9780470570418
- Summary
- Chapter
- References
Keywords:
- single-gene and whole-genome duplications and protein–protein interaction network evolution;
- gene duplications, point mutations, and domain rearrangements - shaping regulatory and protein interaction networks;
- dimerization, formation of functional protein complex of two subunits
Summary
This chapter contains sections titled:
Introduction
Evolution of PINs
Single-Gene Duplications
Whole-Genome Duplications
Diploidization Phase
Dosage Balance Hypothesis
Types of Interactions
WGDs, Transient Interactions, and Organismal Complexity
Studies on PPIs of Ohnologues
Concerns About the Methods of Analysis and the Quality of the Data
The Importance of Medium-Scale Studies: the Case of Dimerization
Evolution of Dimerization Networks
Conclusions
Acknowledgment
References