Clinical Trials on Cognitive Drugs
Published Online: 15 MAR 2010
Copyright © 2010 John Wiley & Sons, Inc. All rights reserved.
Pharmaceutical Sciences Encyclopedia
How to Cite
Farina, E. and Baglio, F. 2010. Clinical Trials on Cognitive Drugs. Pharmaceutical Sciences Encyclopedia. 230:1–28.
- Published Online: 15 MAR 2010
Cognitive disabilities, especially memory disturbances and cognitive deficits, posttraumatic brain injury (TBI), and poststroke are important targets for clinical pharmacological trials due to their important epidemiological and social impact. Brain changes leading to cognitive decline and dementia, and their relation to disability, are key topics requiring investigation at the population level. It is expected that pharmacological approaches will become increasingly integrated with behavioral, genetic, and neuroimaging methods to investigate disease processes and the normal and preclinical individual differences that underlie successful— or unsuccessful—aging.
- safety evaluation;