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Vaginal Drug Delivery

Pharmaceutical Manufacturing: Production and Processes

  1. José das Neves,
  2. Maria Helena Amaral,
  3. Maria Fernanda Bahia

Published Online: 15 MAR 2010

DOI: 10.1002/9780470571224.pse361

Pharmaceutical Sciences Encyclopedia

Pharmaceutical Sciences Encyclopedia

How to Cite

das Neves, J., Amaral, M. H. and Bahia, M. F. 2010. Vaginal Drug Delivery. Pharmaceutical Sciences Encyclopedia. 22:1–70.

Author Information

  1. University of Porto, Porto, Portugal

Publication History

  1. Published Online: 15 MAR 2010


The vagina has been used for a long time as a route for drug administration. Vaginal drug delivery has seen recent advances that make it very promising, in particular therapeutic fields such as the prevention of human immunodeficiency virus (HIV) and other sexually transmitted infections, and contraception. This article discusses the main features of vaginal anatomy, physiology, and histology related to drug delivery as well as vaginal drug delivery systems and their evaluation, current usage of the vagina as a route of drug administration, and promising strategies in this field.


  • vagina;
  • vaginal drug delivery;
  • human immunodeficiency virus (HIV);
  • sexually transmitted infections