13. High-Throughput Screening

  1. Ge Wu

Published Online: 16 JUN 2010

DOI: 10.1002/9780470583128.ch13

Assay Development: Fundamentals and Practices

Assay Development: Fundamentals and Practices

How to Cite

Wu, G. (2010) High-Throughput Screening, in Assay Development: Fundamentals and Practices, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470583128.ch13

Author Information

  1. La Canada Flintridge, California, USA

Publication History

  1. Published Online: 16 JUN 2010
  2. Published Print: 29 MAR 2010

ISBN Information

Print ISBN: 9780470191156

Online ISBN: 9780470583128



  • High-throughput screening (HTS) - enabling testing of large number of samples;
  • software module in HTS operation - with software controlling HTS work flow;
  • HTS operation management - running HTS, functioning as an operation


This chapter contains sections titled:

  • Introduction

  • Molecular or Cellular Targets and Assay Development

  • Compound Library Management

  • Hardware Module

  • Software Module

  • HTS Operation Management

  • Building an HTS Operation for Biopharmaceutical Discovery

  • Quality Control and Data Analysis in Primary Screening

  • Useful Websites

  • Bibliography