1. TRP Channels and Human Diseases

  1. Arthur Gomtsyan and
  2. Connie R. Faltynek
  1. Bernd Nilius and
  2. Rudi Vennekens

Published Online: 22 FEB 2010

DOI: 10.1002/9780470588284.ch1

Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders

Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders

How to Cite

Nilius, B. and Vennekens, R. (2010) TRP Channels and Human Diseases, in Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders (eds A. Gomtsyan and C. R. Faltynek), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470588284.ch1

Editor Information

  1. Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL, USA

Author Information

  1. KU Leuven, Department of Molecular Cell Biology, Laboratory Ion Channel Research, Campus Gasthuisberg, Leuven, Belgium

Publication History

  1. Published Online: 22 FEB 2010
  2. Published Print: 12 FEB 2010

ISBN Information

Print ISBN: 9780470175576

Online ISBN: 9780470588284

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Keywords:

  • vanilloid receptor TRPV1 in drug discovery and TRP cation channels, polymodal cell sensors;
  • transient receptor potential (TRP) channels and human diseases;
  • TRP channels, tools identifying new pathomechanisms - promising targets for new pharmacological developments

Summary

This chapter contains sections titled:

  • Introduction

  • The “Canonical” TRPCS

  • The TRPV Subfamily

  • The TRPM Subfamily

  • TRPA

  • The TRPML Subfamily

  • The TRPP Subfamily

  • Conclusions

  • References