12. 2-Pyridinylpiperazine Carboxamide Class and Related TRPV1 Antagonists

  1. Arthur Gomtsyan and
  2. Connie R. Faltynek
  1. Natalie A. Hawryluk and
  2. Nicholas I. Carruthers

Published Online: 22 FEB 2010

DOI: 10.1002/9780470588284.ch12

Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders

Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders

How to Cite

Hawryluk, N. A. and Carruthers, N. I. (2010) 2-Pyridinylpiperazine Carboxamide Class and Related TRPV1 Antagonists, in Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders (eds A. Gomtsyan and C. R. Faltynek), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470588284.ch12

Editor Information

  1. Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL, USA

Author Information

  1. Johnson & Johnson Pharmaceutical Research & Development, L.L.C. San Diego, CA, USA

Publication History

  1. Published Online: 22 FEB 2010
  2. Published Print: 12 FEB 2010

ISBN Information

Print ISBN: 9780470175576

Online ISBN: 9780470588284

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Keywords:

  • 2- pyridinylpiperazine carboxamides - one of the first classes of high-affinity TRPV1 antagonists;
  • 2-pyridinylpiperazine carboxamide CL;
  • progression of piperazine core structures to amino quinazolines

Summary

This chapter contains sections titled:

  • Introduction

  • Conclusion

  • References