Chapter 2. Role of TRP Channels in Pain: An Overview
- Arthur Gomtsyan,
- Connie R. Faltynek
Published Online: 22 FEB 2010
DOI: 10.1002/9780470588284.ch2
Copyright © 2010 John Wiley & Sons, Inc.
Book Title
Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders
Additional Information
How to Cite
Szallasi, A. (2010) Role of TRP Channels in Pain: An Overview, in Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders (eds A. Gomtsyan and C. R. Faltynek), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470588284.ch2
Editor Information
Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL, USA
Publication History
- Published Online: 22 FEB 2010
- Published Print: 12 FEB 2010
ISBN Information
Print ISBN: 9780470175576
Online ISBN: 9780470588284
- Summary
- Chapter
- References
Keywords:
- role of TRP channels in pain;
- emerging role of TRP channels in visceral pain;
- targeting TRP channels on nociceptors - attractive new and logical strategy in drug development
Summary
This chapter contains sections titled:
Introduction
The Central Role of TRP Channels in Nociception and Inflammatory Pain
The Emerging Role of TRP Channels in Visceral Pain
Contribution of TRP Channels to Neuropathic Pain, Cancer Pain, and Migraine
Differential TRP Channel Expression Defines Functional Sensory Neuron Subtypes: Implications for Drug development
Taking a Short TR(i)P beyond Pain
Disease - Related Changes in TRP Channel Expression: a New Spin Complicating Drug Development
TRPS on Nociceptive Neurons as Targets for Novel Analgesic Drugs: Attractive but not so Innocent
Concluding Remarks
References