3. Biochemical Pharmacology of TRPV1: Molecular Integrator of Pain Signals

  1. Arthur Gomtsyan and
  2. Connie R. Faltynek
  1. Carol S. Surowy,
  2. Philip R. Kym and
  3. Regina M. Reilly

Published Online: 22 FEB 2010

DOI: 10.1002/9780470588284.ch3

Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders

Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders

How to Cite

Surowy, C. S., Kym, P. R. and Reilly, R. M. (2010) Biochemical Pharmacology of TRPV1: Molecular Integrator of Pain Signals, in Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders (eds A. Gomtsyan and C. R. Faltynek), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470588284.ch3

Editor Information

  1. Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL, USA

Author Information

  1. Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL, USA

Publication History

  1. Published Online: 22 FEB 2010
  2. Published Print: 12 FEB 2010

ISBN Information

Print ISBN: 9780470175576

Online ISBN: 9780470588284

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Keywords:

  • biochemical pharmacology of TRPV1 - molecular integrator of pain signals;
  • activation of TRPV1—a polymodal receptor;
  • polymodal activation of TRPV1 - major role as molecular integrator of pain signals

Summary

This chapter contains sections titled:

  • Introduction

  • TRPV1 Structure

  • Activation of TRPV1—A Polymodal Receptor

  • TRPV1 as a Molecular Integrator

  • Trafficking

  • Summary

  • References