Chapter 4. TRPV1 Genetics
- Arthur Gomtsyan,
- Connie R. Faltynek
Published Online: 22 FEB 2010
DOI: 10.1002/9780470588284.ch4
Copyright © 2010 John Wiley & Sons, Inc.
Book Title
Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders
Additional Information
How to Cite
Dorfman, R., Tsui, H., Salter, M. W. and Dosch, H.-M. (2010) TRPV1 Genetics, in Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders (eds A. Gomtsyan and C. R. Faltynek), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470588284.ch4
Editor Information
Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL, USA
Publication History
- Published Online: 22 FEB 2010
- Published Print: 12 FEB 2010
ISBN Information
Print ISBN: 9780470175576
Online ISBN: 9780470588284
- Summary
- Chapter
- References
Keywords:
- TRPV1 genetics;
- functional TRPV1 differences in nonconserved amino acid positions;
- functional polymorphisms in human trpv1 gene
Summary
This chapter contains sections titled:
Overview
trpv1 GENE STRUCTURE in different Species
Alternative Splicing of trpv1 Results in different Functional Variants
Functional TRPV1 differences in Nonconserved Amino Acid Positions
Structure – Function Analysis
Missense Mutations in Non-Obese Diabetic (NOD) Mice affect TRPV1 Function and Cause Diabetes
Functional Polymorphisms in the Human trpv1 Gene
Selection Pressure on Human trpv1 Gene?
Rare Variants of the Human trpv1 Gene
References