Chapter 9. TRPV1 Receptors and Migraine

  1. Arthur Gomtsyan,
  2. Connie R. Faltynek
  1. Philip R. Holland,
  2. Peter J. Goadsby

Published Online: 22 FEB 2010

DOI: 10.1002/9780470588284.ch9

Book Title

Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders

Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders

Additional Information

How to Cite

Holland, P. R. and Goadsby, P. J. (2010) TRPV1 Receptors and Migraine, in Vanilloid Receptor TRPV1 in Drug Discovery: Targeting Pain and Other Pathological Disorders (eds A. Gomtsyan and C. R. Faltynek), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470588284.ch9

Editor Information

  1. Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL, USA

Author Information

  1. Headache Group Department of Neurology University of California, San Francisco, CA, USA

Publication History

  1. Published Online: 22 FEB 2010
  2. Published Print: 12 FEB 2010

ISBN Information

Print ISBN: 9780470175576

Online ISBN: 9780470588284

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Keywords:

  • TRPV1 receptors and migraine;
  • migraine therapy - split into two modalities, prophylactic or acute;
  • TRPV1 possible interaction with other systems

Summary

This chapter contains sections titled:

  • Introduction

  • Current Migraine Treatment

  • Migraine and Triptans

  • Calcitonin Gene - Related Peptide (CGRP) and Migraine

  • Genetics of Migraine

  • Pathophysiology

  • TRPV1 Receptor Antagonists as a Novel Treatment Strategy in Migraine

  • TRPV1 and CGRP

  • TRPV1 Possible Interaction with other Systems

  • Clinical Data

  • References

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