10. Time-of-Flight Mass Spectrometry

  1. Richard B. Cole
  1. Robert J. Cotter

Published Online: 27 NOV 2012

DOI: 10.1002/9780470588901.ch10

Electrospray and MALDI Mass Spectrometry: Fundamentals, Instrumentation, Practicalities, and Biological Applications, Second Edition

Electrospray and MALDI Mass Spectrometry: Fundamentals, Instrumentation, Practicalities, and Biological Applications, Second Edition

How to Cite

Cotter, R. J. (2010) Time-of-Flight Mass Spectrometry, in Electrospray and MALDI Mass Spectrometry: Fundamentals, Instrumentation, Practicalities, and Biological Applications, Second Edition (ed R. B. Cole), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470588901.ch10

Publication History

  1. Published Online: 27 NOV 2012
  2. Published Print: 9 APR 2010

ISBN Information

Print ISBN: 9780471741077

Online ISBN: 9780470588901

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Keywords:

  • mass resolution;
  • spatial distribution;
  • kinetic energy;
  • time-lag focusing;
  • orthogonal acceleration

Summary

This chapter contains sections titled:

  • Then and Now

  • The Question of Mass Resolution

  • Reflectron Time-of-Flight (RTOF) Instruments

  • Ionizing Biomolecules Directly from Surfaces: LD and MALDI

  • Fragmentation and Tandem TOF Mass Spectrometry

  • Orthogonal Acceleration and Hybrid Instruments

  • Summary and Future Prospects