23. The Impact of Formulation and Drying Processes on the Characteristics and Performance of Biopharmaceutical Powders

  1. Feroz Jameel3 and
  2. Susan Hershenson4
  1. Vu L. Truong1 and
  2. Ahmad M. Abdul-Fattah2

Published Online: 5 AUG 2010

DOI: 10.1002/9780470595886.ch23

Formulation and Process Development Strategies for Manufacturing Biopharmaceuticals

Formulation and Process Development Strategies for Manufacturing Biopharmaceuticals

How to Cite

Truong, V. L. and Abdul-Fattah, A. M. (2010) The Impact of Formulation and Drying Processes on the Characteristics and Performance of Biopharmaceutical Powders, in Formulation and Process Development Strategies for Manufacturing Biopharmaceuticals (eds F. Jameel and S. Hershenson), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470595886.ch23

Editor Information

  1. 3

    Drug Product and Device Development, Amgen Inc., Thousand Oaks, California, USA

  2. 4

    Pharmaceutical and Device Development, Genentech Inc., South San Francisco, California, USA

Author Information

  1. 1

    Aridis Pharmaceuticals, San Jose, California, USA

  2. 2

    Biogen Idec, San Jose, California, USA

Publication History

  1. Published Online: 5 AUG 2010
  2. Published Print: 26 JUL 2010

ISBN Information

Print ISBN: 9780470118122

Online ISBN: 9780470595886

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Keywords:

  • impact of formulation and drying processes - and performance of biopharmaceutical powders;
  • formulation and drying-induced variations - affecting storage stability of biopharmaceuticals in glassy state;
  • optimizing drying method and formulation - optimizing solid-state properties

Summary

This chapter contains sections titled:

  • Introduction

  • The Impact of Formulation on Solid-State Properties and Storage Stability of Biopharmaceuticals

  • Impact of Drying Method on Solid-State Properties and Storage Stability of Biopharmaceuticals

  • The Future—Optimizing Drying Method and Formulation to Optimize Solid-State Properties

  • References