8. Statistics and Decision Making in Adaptive Research

  1. Michael J. Rosenberg

Published Online: 23 FEB 2010

DOI: 10.1002/9780470599686.ch8

The Agile Approach to Adaptive Research: Optimizing Efficiency in Clinical Development

The Agile Approach to Adaptive Research: Optimizing Efficiency in Clinical Development

How to Cite

Rosenberg, M. J. (2010) Statistics and Decision Making in Adaptive Research, in The Agile Approach to Adaptive Research: Optimizing Efficiency in Clinical Development, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470599686.ch8

Publication History

  1. Published Online: 23 FEB 2010
  2. Published Print: 25 JAN 2010

ISBN Information

Print ISBN: 9780470247518

Online ISBN: 9780470599686

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Keywords:

  • decision making;
  • adaptive research;
  • frequentist approach;
  • Bayesian approach;
  • prior distributions

Summary

This chapter contains sections titled:

  • The Frequentist Approach

  • The Bayesian Approach

  • Comparing Bayesian and Frequentist Methods

  • Prior Distributions

  • The Pharma Context

  • Conclusions

  • Frequentists, Bayesians, and Pragmatists