3. Prediction of Pharmacokinetics and Drug Safety in Humans

  1. Mitchell N. Cayen
  1. Peter L. Bullock

Published Online: 3 AUG 2010

DOI: 10.1002/9780470613191.ch3

Early Drug Development

Early Drug Development

How to Cite

Bullock, P. L. (2010) Prediction of Pharmacokinetics and Drug Safety in Humans, in Early Drug Development (ed M. N. Cayen), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470613191.ch3

Editor Information

  1. Cayen Pharmaceutical Consulting, LLC, Bedminster, New Jersey, USA

Author Information

  1. Paul P. Carbone Cancer Center, University of Wisconsin, Madison, Wisconsin, USA

Publication History

  1. Published Online: 3 AUG 2010
  2. Published Print: 23 JUL 2010

ISBN Information

Print ISBN: 9780470170861

Online ISBN: 9780470613191



  • pharmacokinetics and drug safety prediction in humans;
  • drug safety prediction for risk assessment - elusive goals related to drug discovery and development;
  • model application in drug prediction pharmacokinetics


This chapter contains sections titled:

  • Introduction

  • Prediction of Human Pharmacokinetic Behavior

  • Prediction of Drug Safety

  • Conclusions

  • References