12. Fate of a Duplicate in a Network Context

  1. Katharina Dittmar2 and
  2. David Liberles3
  1. Orkun S. Soyer

Published Online: 14 MAR 2011

DOI: 10.1002/9780470619902.ch12

Evolution after Gene Duplication

Evolution after Gene Duplication

How to Cite

Soyer, O. S. (2010) Fate of a Duplicate in a Network Context, in Evolution after Gene Duplication (eds K. Dittmar and D. Liberles), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470619902.ch12

Editor Information

  1. 2

    Department of Biological Sciences, SUNY at Buffalo, Buffalo, New York, USA

  2. 3

    Department of Molecular Biology, University of Wyoming, Laramie, Wyoming, USA

Author Information

  1. Engineering, Mathematics and Physical Sciences, University of Exeter, Exeter, UK

Publication History

  1. Published Online: 14 MAR 2011
  2. Published Print: 20 SEP 2010

ISBN Information

Print ISBN: 9780470593820

Online ISBN: 9780470619902



  • fate of a duplicate in a network context - genes as part of a larger system, hypothetical evolutionary routes following a duplication event in a signaling network;
  • dynamics and evolution at network level - fate of a duplicate gene in context of a larger system of which it is part, modeling dynamics and evolution of systems;
  • duplicate retention and robustness - ability of a system to maintain its function, in the face of perturbations


This chapter contains sections titled:

  • Introduction

  • Genes as Part of a Larger System

  • Studying Dynamics and Evolution at the Network Level

  • Reconsidering Fitness Effects of Duplications in the Context of Networks

  • Fate of a Gene Duplicate in a Network Context

  • Duplicate Retention and Robustness

  • Toward a Complete Model of Gene Duplication

  • References