Chapter 14. Experimental Animal Studies and Carcinogenicity

  1. Ching-Hung Hsu and
  2. Todd Stedeford
  1. Mary Elizabeth (Bette) Meek

Published Online: 5 AUG 2010

DOI: 10.1002/9780470622728.ch14

Cancer Risk Assessment

Cancer Risk Assessment

How to Cite

Meek, M. E. (2010) Experimental Animal Studies and Carcinogenicity, in Cancer Risk Assessment (eds C.-H. Hsu and T. Stedeford), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470622728.ch14

Editor Information

  1. Health, Safety & Environment, Albemarle Corporation, Baton Rouge, Louisiana, USA

Author Information

  1. Chemical Risk Assessment, McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, Ottawa, Ontario, Canada

Publication History

  1. Published Online: 5 AUG 2010
  2. Published Print: 6 JUL 2010

ISBN Information

Print ISBN: 9780470238226

Online ISBN: 9780470622728



  • experimental animal studies and carcinogenicity;
  • hazard identification for cancer, objective and design of combined chronic/cancer bioassay - in rats and mice;
  • application in risk assessment and hazard identification


This chapter contains sections titled:

  • Introduction

  • Current Status of Hazard Testing for Cancer for Regulatory Risk Assessment

  • Application in Risk Assessment

  • Evolution of Testing Strategies

  • Discussion: Closing the GAP Between Hazard Testing and Risk Assessment

  • References