Chapter 23. Computational Toxicology in Cancer Risk Assessment

  1. Ching-Hung Hsu and
  2. Todd Stedeford
  1. Jerry N. Blancato

Published Online: 5 AUG 2010

DOI: 10.1002/9780470622728.ch23

Cancer Risk Assessment

Cancer Risk Assessment

How to Cite

Blancato, J. N. (2010) Computational Toxicology in Cancer Risk Assessment, in Cancer Risk Assessment (eds C.-H. Hsu and T. Stedeford), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470622728.ch23

Editor Information

  1. Health, Safety & Environment, Albemarle Corporation, Baton Rouge, Louisiana, USA

Author Information

  1. Office of Administrative and Research Support, Office of Research and Development (ORD), United States Environmental Protection Agency, Research Triangle Park, North Carolina, USA

Publication History

  1. Published Online: 5 AUG 2010
  2. Published Print: 6 JUL 2010

ISBN Information

Print ISBN: 9780470238226

Online ISBN: 9780470622728



  • computational toxicology in cancer risk assessment - advent of high-throughput screening (HTS) studies and high content analysis (HCA);
  • PBPK modeling application - to better understand disposition of potentially toxic compounds;
  • computational toxicology and future risk assessments


This chapter contains sections titled:

  • Introduction

  • Risk Assessment: Historical Perspective

  • Enhancements in Quantitative Risk Assessment

  • Computational Toxicology and Future Risk Assessments

  • Conclusion

  • References