Chapter 27. Cancer Risk Assessment: More Uncertain than We Thought

  1. Ching-Hung Hsu and
  2. Todd Stedeford
  1. Edmund A. C. Crouch

Published Online: 5 AUG 2010

DOI: 10.1002/9780470622728.ch27

Cancer Risk Assessment

Cancer Risk Assessment

How to Cite

Crouch, E. A. C. (2010) Cancer Risk Assessment: More Uncertain than We Thought, in Cancer Risk Assessment (eds C.-H. Hsu and T. Stedeford), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470622728.ch27

Editor Information

  1. Health, Safety & Environment, Albemarle Corporation, Baton Rouge, Louisiana, USA

Author Information

  1. Cambridge Environmental, Inc., Cambridge, Massachusetts, USA

Publication History

  1. Published Online: 5 AUG 2010
  2. Published Print: 6 JUL 2010

ISBN Information

Print ISBN: 9780470238226

Online ISBN: 9780470622728



  • cancer risk assessment - more uncertain than we thought;
  • evaluation of uncertainty in cancer risk assessment - using CD10 measure;
  • median CD10 for chemical within a species - extrapolated between species, with associated lognormal uncertainty distribution


This chapter contains sections titled:

  • Introduction

  • Summary of Previous Analyses

  • Selection of Carcinogenicity Measure—The CD10

  • The Variation of CD10 Within a Species

  • Extrapolation of the Median CD10 Between Species

  • Extrapolation of the IntraSpecies Variation in CD10

  • Conclusions

  • Appendix

  • References