Chapter 1. Chapter 1. Skeletal Morphogenesis and Embryonic Development

  1. ASBMR
  1. Yingzi Yang

Published Online: 23 DEC 2009

DOI: 10.1002/9780470623992.ch1

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism

How to Cite

ASBMR (2008) Chapter 1. Skeletal Morphogenesis and Embryonic Development, in Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470623992.ch1

Publication History

  1. Published Online: 23 DEC 2009
  2. Published Print: 18 NOV 2008

ISBN Information

Print ISBN: 9780977888214

Online ISBN: 9780470623992

SEARCH

Keywords:

  • bone;
  • cartilage;
  • embryonic development;
  • chondrocyte;
  • osteoblast;
  • cell signaling;
  • skeletal development;
  • pattern formation PTH-related peptide;
  • Ihh;
  • Wnt;
  • fibroblast growth factor;
  • bone morphogenetic protein;
  • retinoic acid;
  • Notch;
  • sox9;
  • Runx2;
  • ossification mechanism;
  • intramembranous ossification;
  • endochondral ossification;
  • chondrocyte proliferation;
  • chondrocyte hypertrophy;
  • somatogenesis;
  • segmentation clock

Summary

This chapter contains sections titled:

  • Introduction

  • Early Skeletal Patterning

  • Embryonic Cartilage and Bone Formation

  • Chondrocyte Proliferation and Differentiation in the Developing Cartilage

  • Regulation of Chondrocyte Survival

  • Conclusions

  • Acknowledgments