Chapter 27. Chapter 27. Ca2±Sensing Receptor

  1. ASBMR
  1. Edward M. Brown

Published Online: 23 DEC 2009

DOI: 10.1002/9780470623992.ch27

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism

How to Cite

ASBMR (2008) Chapter 27. Ca2±Sensing Receptor, in Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470623992.ch27

Publication History

  1. Published Online: 23 DEC 2009
  2. Published Print: 18 NOV 2008

ISBN Information

Print ISBN: 9780977888214

Online ISBN: 9780470623992

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Keywords:

  • Ca2+-sensing receptor;
  • parathyroid;
  • C-cell;
  • kidney;
  • intestine;
  • PTH;
  • calcitonin;
  • bone;
  • cartilage;
  • G protein–coupled receptor;
  • signal transduction

Summary

This chapter contains sections titled:

  • Introduction

  • Isolation and Properties of the CaSR

  • Intracellular Signaling by the CaSR

  • Casr Gene and its Regulation

  • Roles of the CaSR in Tissues Maintaining Ca2+o Homeostasis

  • C-cells

  • CaSR Integrates Ca2+o and Water Metabolism

  • Other Agonists and Modulators of the CaSR