Chapter 28. Chapter 28. Vitamin D: Production, Metabolism, Mechanism of Action, and Clinical Requirements

  1. ASBMR
  1. Daniel Bikle1,
  2. John Adams2 and
  3. Sylvia Christakos3

Published Online: 23 DEC 2009

DOI: 10.1002/9780470623992.ch28

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism

How to Cite

ASBMR (2009) Chapter 28. Vitamin D: Production, Metabolism, Mechanism of Action, and Clinical Requirements, in Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470623992.ch28

Author Information

  1. 1

    Veteran Affairs Medical Center and Department of Medicine and Dermatology, University of California, San Francisco, California

  2. 2

    Orthopaedic Hospital, University of California, Los Angeles, California

  3. 3

    Department of Biochemistry and Molecular Biology, New Jersey Medical School, Newark, New Jersey

Publication History

  1. Published Online: 23 DEC 2009
  2. Published Print: 18 NOV 2008

ISBN Information

Print ISBN: 9780977888214

Online ISBN: 9780470623992

SEARCH

Keywords:

  • vitamin D;
  • bone;
  • intestine;
  • kidney;
  • osteomalacia;
  • immune function;
  • keratinocytes;
  • vitamin D metabolism;
  • vitamin D mechanism of action;
  • cancer;
  • malabsorption

Summary

This chapter contains sections titled:

  • Vitamin D3 Production

  • Vitamin D Metabolism

  • Transport of Vitamin D in the Blood

  • Internalization of Vitamin D Metabolites

  • Mechanism of Action

  • Overview of Vitamin D Regulation of Calcium and Phosphate Metabolism

  • Classic Target Tissues

  • Nonclassical Target Tissues

  • Immunobiology of Vitamin D

  • Keratinocyte Function in Epidermis and Hair Follicles

  • Nutritional Considerations