Chapter 34. Chapter 34. Biochemical Markers of Bone Turnover in Osteoporosis

  1. ASBMR
  1. Pawel Szulc and
  2. Pierre D. Delmas

Published Online: 23 DEC 2009

DOI: 10.1002/9780470623992.ch34

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism

How to Cite

ASBMR (2008) Chapter 34. Biochemical Markers of Bone Turnover in Osteoporosis, in Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470623992.ch34

Publication History

  1. Published Online: 23 DEC 2009
  2. Published Print: 18 NOV 2008

ISBN Information

Print ISBN: 9780977888214

Online ISBN: 9780470623992

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Keywords:

  • bone turnover;
  • osteocalcin;
  • C-terminal cross-linking telopeptides of type I collagen;
  • deoxypyridinoline;
  • osteoporosis

Summary

This chapter contains sections titled:

  • Introduction

  • General Limitations of BTMS and their Analytical and Preanalytical Variability

  • Selected Determinants of the Preanalytical Variability

  • Changes in BTM Levels after Menopause

  • Association Between BTM Levels and Rate of Bone Loss

  • Association Between Bone Turnover Rate and Risk of Fracture

  • Biochemical BTMs and Anti-Osteoporotic Treatment

  • Metabolic Effect of Anti-Osteoporotic Treatment

  • Dose-Finding Studies

  • Decrease in BTM Levels and Antifracture Efficacy of Antiresorptive Treatment

  • BTM Levels and Antifracture Efficacy of Bone Formation-Stimulating Treatment

  • Changes in Bone Turnover after Discontinuation of Anti-Osteoporotic Treatment

  • Combination Therapy and BTMs

  • Association Between BTM Levels and Adherence with Antiresorptive Treatment

  • BTMs in Men

  • Effect of Anti-Osteoporotic Treatment on BTM in MEN

  • Conclusions